Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
Our findings reveal distinct circulating EV-miRNA expression patterns in AIS patients from Qatar, highlighting potential biomarkers that could aid in stroke diagnosis and therapeutic strategies. The identified miRNAs are involved in critical cellular pathways, offering novel insights into the molecular mechanisms underlying stroke pathology. Circulating EV-miRNAs differentially expressed in AIS may have a pathophysiological role and may guide further research to elucidate their precise mechanisms.
Authors
- Ghulam Jeelani Pir (ORCID: https://orcid.org/0000-0002-3147-8141)
- Sajitha V. Pananchikkal
- Sujata Joseph
- Muhammad Zahid (ORCID: https://orcid.org/0000-0002-7222-6776)
- Ahmed Own
- Ashfaq M Shuaib (ORCID: https://orcid.org/0000-0002-3380-7068)
- Aijaz Parray
- Naveed Akhtar (ORCID: https://orcid.org/0000-0003-3406-673X)
- Raheem Ayadathil (ORCID: https://orcid.org/0000-0003-2816-5563)
- Reny Francis
- Blessy Babu
- Abdelali Agouni (ORCID: https://orcid.org/0000-0002-8363-1582)
- Deborah M. Morgan
- Ryan Ty Ui
- S Sivasankaran
Institutions
- University of Alberta (CA)
- Hamad Medical Corporation (QA)
- Qatar University (QA)
Publication Details
- Journal
- Brain Research
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1016/j.brainres.2024.149171
- Citations
- 13
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Fonds National de la Recherche Luxembourg
- Qatar University
- Qatar National Research Fund