β,β-Dimethylacrylalkannin, a key component of Zicao, induces cell cycle arrest and necrosis in hepatocellular carcinoma cells
This study underscores DMAKN's pivotal role as the principal anti-HCC compound in Zicao, delineating its differential effects and underlying mechanisms. These results demonstrate the potential of DMAKN as a therapeutic agent for the treatment of HCC, providing important information for further study and advancement in cancer therapy.
Authors
- Rui‐Hong Gong (ORCID: https://orcid.org/0000-0002-4555-0394)
- Zesi Lin
- Jiawen Chen (ORCID: https://orcid.org/0000-0003-1233-5599)
- Sibao Chen (ORCID: https://orcid.org/0000-0003-1539-9192)
- Lisha Shen (ORCID: https://orcid.org/0000-0002-1808-6370)
- Guoqing Chen (ORCID: https://orcid.org/0000-0002-3671-5257)
- Yu-Shan Lin
- Yong Yang
- Xing-Fang Qiao
- Qian-Mei Hu
Institutions
- Hong Kong Polytechnic University (HK)
- Shenzhen Polytechnic University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- TCM-Intigrated Cancer Center of Southern Medical University (CN)
- Chongqing Academy of Chinese Materia Medica (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1016/j.phymed.2024.155959
- Citations
- 7
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.19