TRIM8 as a predictor for prognosis in childhood acute lymphoblastic leukemia based on a signature of neutrophil extracellular traps
We identified a novelty in a prognostic model that could aid in the development of personalized treatments for cALL patients. Furthermore, it revealed that the expression of TRIM8 is a contributing factor to the proliferation of leukemia cells and worsens the prognosis of cALL.
Authors
- Uet Yu (ORCID: https://orcid.org/0000-0003-4391-3398)
- Sixi Liu
- Jiayin Zheng (ORCID: https://orcid.org/0000-0002-5559-6847)
- Ying Wang (ORCID: https://orcid.org/0000-0002-7852-386X)
- Mengyun Xie
- Kexin Sun
- Cuilan Xiao
- Yijun Zhao
- Waihin Tin
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- Guangdong Pharmaceutical University (CN)
- Hainan Maternal and Child Health Hospital (CN)
- Sun Yat-sen Memorial Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Shenzhen Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-08-19
- DOI
- https://doi.org/10.3389/fonc.2024.1427776
- Citations
- 5
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Science, Technology and Innovation Commission of Shenzhen Municipality
- Sanming Project of Medicine in Shenzhen