Evolutionary dependency of cancer mutations in gene pairs inferred by nonsynonymous-synonymous mutation ratios
We propose that the ED of gene pairs evaluated by dNdS ratios can advance our understanding of the functional relationship of genes with potential biological and clinical implications.
Authors
- Youngbeen Moon (ORCID: https://orcid.org/0009-0008-9046-076X)
- Hae Jin Cho (ORCID: https://orcid.org/0000-0003-3041-5824)
- Ruibin Xi (ORCID: https://orcid.org/0000-0001-7545-7361)
- Hye Young Jeong (ORCID: https://orcid.org/0000-0003-3390-376X)
- Jinseon Yoo (ORCID: https://orcid.org/0000-0002-3210-6374)
- Seungho Lee (ORCID: https://orcid.org/0000-0001-7069-267X)
- Jaehoon Kim (ORCID: https://orcid.org/0000-0001-6171-9914)
- Seo‐Young Lee (ORCID: https://orcid.org/0000-0001-5319-1777)
- Sunmin Kim (ORCID: https://orcid.org/0000-0002-3855-8785)
- Tae‐Min Kim (ORCID: https://orcid.org/0000-0002-7993-9701)
- Dongjin Han (ORCID: https://orcid.org/0000-0003-1093-1741)
- Jeong Yang Jeon
- Su Jung Kang
- Byeong Chang Sim
Institutions
- Catholic Medical Center (US)
- Yonsei University (KR)
- Peking University (CN)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Genome Medicine
- Published
- 2024-08-19
- DOI
- https://doi.org/10.1186/s13073-024-01376-7
- Citations
- 3
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea