The impact and mechanism study of Sijunzi decoction and Rg1 on proliferation and differentiation of human umbilical cord mesenchymal stem cells: An experimental study
Sijunzi decoction promotes the proliferation and osteogenic differentiation of hUC-MSCs, potentially through the activation of the HIF-1α signaling pathway and by modulating the microenvironment via reducing inflammation and oxidative stress levels. Rg1 might be involved in this process.
Authors
- Yafei Lu (ORCID: https://orcid.org/0009-0000-6931-2852)
- Weina Zhu (ORCID: https://orcid.org/0000-0001-9836-896X)
- Shaohua Huangfu
- Ying Zhou (ORCID: https://orcid.org/0000-0001-7319-609X)
- Chungen Zhou
- Min Li (ORCID: https://orcid.org/0000-0002-7113-2700)
- Yajie Zhang (ORCID: https://orcid.org/0000-0001-5570-5436)
- Fuhao Qin
- Bin Jiang (ORCID: https://orcid.org/0000-0002-4622-9703)
- Chuanxue Ma
- Jianmin Wang
Institutions
- Nanjing University of Chinese Medicine (CN)
- Anhui University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Medicine
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1097/md.0000000000039350
- Citations
- 3
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.31