Development and Characterization of Silver Doped Hydroxyapatite/Chitosan Nanobiocomposites

Abstract The aim of this study is to develop a new nanobiocomposite based on silver doped hydroxyapatite (AgHAp)/chitosan (CH), AgHAp‐CH ( x Ag = 0.15) by an adapted method. The obtained nanobiocomposites are studied by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) studies. The good stability of AgHAp‐CH suspension is established by ultrasound and zeta potential measurements. More than that, the antimicrobial activity of AgHAp‐CH nanobiocomposites against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, and Candida albicans ATCC 10231 microbial strains is evaluated. AgHAp‐CH nanobiocomposites demonstrate an effective antibacterial effect against the studied microbial strains. Considering the facile method involved in the development of these nanobiomaterials and their excellent properties, it is suggested that they can be suitable candidates for applications in the biomedical field.