Why Biopolymer Microgels with Dynamically Switchable Properties Would be a Great Tool‐Box for the Cultivation of Stem Cells

Abstract In this short perspective article, it is asked why – different from their macroscopic bulk counterparts – biopolymer‐based microgels with dynamically switchable mechanical properties are basically non‐existent. The article pinpoints why such dynamic control over the viscoelasticity of microgels would be desirable for the encapsulation of stem cells, how switchable mechanical properties may be achievable in biopolymer‐based microgel systems, and what pitfalls and issues need to be addressed to realize such a complex, engineered microenvironment for cells.

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Publication Details

Journal
Advanced Materials Interfaces
Published
2024-08-16
DOI
https://doi.org/10.1002/admi.202400354
Citations
2
Primary Topic
3D Printing in Biomedical Research
Type
article
Field-Weighted Citation Impact
0.37

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article

Why Biopolymer Microgels with Dynamically Switchable Properties Would be a Great Tool‐Box for the Cultivation of Stem Cells

Oliver Lieleg, Berna Özkale
2 citations
Advanced Materials Interfaces
3D Printing in Biomedical Research
0.37
article

Why Biopolymer Microgels with Dynamically Switchable Properties Would be a Great Tool‐Box for the Cultivation of Stem Cells

Oliver Lieleg, Berna Özkale
article en
2 citations

Abstract

Abstract In this short perspective article, it is asked why – different from their macroscopic bulk counterparts – biopolymer‐based microgels with dynamically switchable mechanical properties are basically non‐existent. The article pinpoints why such dynamic control over the viscoelasticity of microgels would be desirable for the encapsulation of stem cells, how switchable mechanical properties may be achievable in biopolymer‐based microgel systems, and what pitfalls and issues need to be addressed to realize such a complex, engineered microenvironment for cells.

Advanced Materials InterfacesVol. 12(4)
Fischer (Germany) (DE), Technical University of Munich (DE)
Australian Government, Bundesministerium für Bildung und Forschung
Openalex Percentile: Top 44%
3D Printing in Biomedical Research
0.37
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