Management of neonatal and infant aortic thrombosis: A single‐center case series

Neonatal and infant aortic thrombosis is a rare albeit life-threatening thrombotic event, particularly seen in premature infants with an arterial catheter in place. We describe our institutional experience and approach to the management of 11 infants with occlusive or nearly occlusive aortic thrombosis. We observed at least partial thrombus resolution in all patients. Complications related to our management included minor bleeding in two children receiving thrombolytic therapy, and two major bleeding events in children receiving anticoagulation alone. Our experience adds to the growing body of evidence that thrombolysis and thrombectomy should be considered in managing neonatal/infant aortic thrombosis.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2024-08-16
DOI
https://doi.org/10.1002/pbc.31283
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

Management of neonatal and infant aortic thrombosis: A single‐center case series

YoungNa Lee‐Kim, Ajibike Lapite, Sarah E. Sartain, Hyojeong Han et al.
Pediatric Blood & Cancer
Blood Coagulation and Thrombosis Mechanisms
article

Management of neonatal and infant aortic thrombosis: A single‐center case series

YoungNa Lee‐Kim, Ajibike Lapite, Sarah E. Sartain, Hyojeong Han, Clay T. Cohen, Mohammad H Abu-Arja
article en

Abstract

Neonatal and infant aortic thrombosis is a rare albeit life-threatening thrombotic event, particularly seen in premature infants with an arterial catheter in place. We describe our institutional experience and approach to the management of 11 infants with occlusive or nearly occlusive aortic thrombosis. We observed at least partial thrombus resolution in all patients. Complications related to our management included minor bleeding in two children receiving thrombolytic therapy, and two major bleeding events in children receiving anticoagulation alone. Our experience adds to the growing body of evidence that thrombolysis and thrombectomy should be considered in managing neonatal/infant aortic thrombosis.

Pediatric Blood & CancerVol. 71(11)
Children's National (US), Baylor College of Medicine (US), Children's Cancer Center (US)
American Society of Hematology, St. Baldrick's Foundation
Good health and well-being
Openalex Percentile: Top 81%
Blood Coagulation and Thrombosis Mechanisms
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Management of neonatal and infant aortic thrombosis: A single‐center case series — YoungNa Lee‐Kim, Ajibike Lapite, et al. · Pediatric Blood & Cancer (2024) | TGRS Research Map | TGRS