Triage performance of PAX1m/JAM3m in opportunistic cervical cancer screening of non‒16/18 human papillomavirus-positive women: a multicenter prospective study in China
In non-16/18 hrHPV(+) women, PAX1<sup>m</sup>/JAM3<sup>m</sup> was superior to cytology for detecting CIN3 + . Compared with LBC ≥ ASCUS, PAX1<sup>m</sup>/JAM3<sup>m</sup>(+) reduced the number of significant referrals to colposcopy without compromising diagnostic sensitivity.
Authors
- Yu‐Ligh Liou (ORCID: https://orcid.org/0000-0003-3994-6250)
- Guangwu Xiong (ORCID: https://orcid.org/0000-0002-4077-6298)
- Xitong Jin (ORCID: https://orcid.org/0000-0002-8561-046X)
- Bingli Qi (ORCID: https://orcid.org/0000-0003-2873-7461)
- Zhe Dong (ORCID: https://orcid.org/0000-0003-0534-6943)
- Huafeng Shou
- Linghua Kong (ORCID: https://orcid.org/0000-0003-0863-9979)
- Yuchong Hu
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-9797-8384)
- Pei Liu (ORCID: https://orcid.org/0000-0002-3795-6140)
- Xiaojing Chen (ORCID: https://orcid.org/0009-0001-5388-7552)
- Lei Li (ORCID: https://orcid.org/0000-0001-9231-3378)
- Jianwei Zhou (ORCID: https://orcid.org/0000-0002-7208-6179)
- Shikai Liu
- Fei Jing (ORCID: https://orcid.org/0000-0002-2039-2684)
- Sijun Zhou
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Peking Union Medical College Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Cangzhou Central Hospital (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- Inner Mongolia People's Hospital (CN)
- Zhejiang Provincial People's Hospital (CN)
- Peking University International Hospital (CN)
- OriginWater (China) (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1186/s13148-024-01731-w
- Citations
- 13
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 5.03
Funders
- China Postdoctoral Science Foundation
- Peking Union Medical College Hospital
- Peking Union Medical College