Clinico - Radiographic Evaluation of Two Forms of PRF along with DFDBA Bone Graft in the Treatment of Periodontal Intrabony Defects

Background: Man's insatiable desire to create the lost part has led to a plethora of opportunities in periodontal regenerative treatment. One such name, platelet -rich fibrin (PRF) is an autologous concentration of human platelets which along with the platelet derived growth factor (PDGF) has been found to be more favourable for periodontal regeneration amongst all the growth factors found in plasma. Objective: The present study was aimed at comparing the clinical and radiographic evaluation of Leukocyte PRF (3000 rpm; 12 minutes) and Advanced PRF (1500 rpm; 14 minutes) along with demineralized freeze dried bone allograft (DFDBA) in the treatment of periodontal intrabony defects. Materials and Methods: Forty chronic periodontitis patients with intrabony defects (IBDs) were randomly treated by L -PRF or A -PRF with DFDBA. Probing pocket depth (PPD), clinical attachment level (CAL) and radiographic bone fill (RBF) were recorded at baseline, three and six months post -surgery. Results: The mean PPD reduction was greater in the A -PRF group (2.43±0.69 mm) than in the L -PRF group (1.65±0.78 mm) and the mean CAL gain were 2.43±0.67, 1.78±0.91 mm respectively. Greater percentage of mean bone fill was found in the A -PRF group (35.27%) compared to the other group (20.71%). Conclusion: Advanced PRF can be used predictably to reconstruct the lost periodontal structures as indicated by PPD reduction, CAL gain, intrabony defect fill and gives more definitive outcome than L -PRF.