Natural Coptidis Rhizoma Nanoparticles Improved the Oral Delivery of Docetaxel
The novel self-assembled nanoparticles considerably enhanced the cellular absorption, solubility, release, metabolic stability, and pharmacokinetics of oral DTX and demonstrated strong cytotoxicity against tumor cell lines.
Authors
- Ding Ding (ORCID: https://orcid.org/0000-0002-4856-4345)
- Bing‐Liang Ma (ORCID: https://orcid.org/0000-0001-7059-9811)
- Dan Ye (ORCID: https://orcid.org/0009-0000-9389-2017)
- Min Zheng (ORCID: https://orcid.org/0000-0001-7610-5448)
- L.Q Chen (ORCID: https://orcid.org/0000-0002-1172-7323)
- Tong Zhang (ORCID: https://orcid.org/0000-0002-2442-8613)
- Qing Zhao
- Lingyun Pan
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Jingzhou Central Hospital (CN)
- Shanghai Zhabei District Shibei Hospital (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-08-01
- DOI
- https://doi.org/10.2147/ijn.s470853
- Citations
- 5
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- National Natural Science Foundation of China