Preparation of kakkatin derivatives and their anti-tumor activity
HK have a significant inhibitory effect on HCC SMMC-7721 cells, and the targets of their action may be PDE3B and NFKB1 proteins in the cAMP pathway, making it a good lead drug for the treatment of HCC.
Authors
- Yan-Qiang Huang (ORCID: https://orcid.org/0000-0002-0867-0178)
- Yu-Ying Jiang (ORCID: https://orcid.org/0009-0006-4996-1365)
- Wen-Ting Zhou
- Hui-Hua Dong
- Jia-Zi Luo
- Xian Wei
Institutions
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
Publication Details
- Journal
- World Journal of Clinical Oncology
- Published
- 2024-08-16
- DOI
- https://doi.org/10.5306/wjco.v15.i8.1078
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.29