Clinical Impact of Microbiome Characteristics in Treatment-Naïve Extranodal NK/T-Cell Lymphoma Patients
ND-ENKTL exhibited an abundance of Enterobacteriaceae and a dominant presence of Escherichia. These microbial characteristics correlated with disease status, treatment outcomes, and PD-L1 expression, suggesting the potential of the ENKTL microbiome as a biomarker and cause of lymphomagenesis, which warrants further exploration.
Authors
- Seok Jin Kim (ORCID: https://orcid.org/0000-0002-2776-4401)
- Woorim Kang (ORCID: https://orcid.org/0009-0005-1604-5785)
- Sang Eun Yoon (ORCID: https://orcid.org/0000-0002-0379-5297)
- Won Seog Kim (ORCID: https://orcid.org/0000-0002-5400-0466)
- Mauricio Chalita (ORCID: https://orcid.org/0000-0002-2173-6688)
- Dong‐Wook Hyun
- Junhun Cho (ORCID: https://orcid.org/0000-0002-6089-9340)
- Jehee Lee (ORCID: https://orcid.org/0000-0001-9144-3648)
- Hyun Kim (ORCID: https://orcid.org/0000-0002-7210-5798)
Institutions
- Samsung Medical Center (KR)
- Bioscience (China) (CN)
- Korea Research Institute of Bioscience and Biotechnology (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2024-08-16
- DOI
- https://doi.org/10.4143/crt.2024.675
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea