Case report: A rare case of malignant solitary fibrous tumor in an adult with an epithelioid pattern in the occipital region
We illustrated a rare case of malignant solitary fibrous tumor (MSFT) with epithelioid morphology in the occipital region of a 59-year-old female, in which a rare NAB2ex7-STAT6 exon15/16 double fusion subtype was detected by the Next-generation sequencing (NGS) and STAT6 immunohistochemistry (IHC) was diffusely and strongly positively expressed, without recurrence after 20 months of postoperative follow-up. The morphological and molecular genetic aspects and the differential diagnosis are described, and the relevant literature was assessed in order to broaden our understanding and diagnostic capability of this malignancy.
Authors
- Xian-bin Tang
- Senyuan Luo
- Yugang Huang (ORCID: https://orcid.org/0000-0002-8184-0794)
- Ke Huang (ORCID: https://orcid.org/0000-0002-9355-7224)
- Wenwen Liu (ORCID: https://orcid.org/0000-0001-7585-2812)
- Lingling Yuan (ORCID: https://orcid.org/0000-0002-3444-1918)
- Xiu-wen Chen
- Yin-hua Hao
Institutions
- Hubei University of Medicine (CN)
- Taihe Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-08-16
- DOI
- https://doi.org/10.3389/fonc.2024.1339582
- Primary Topic
- Soft tissue tumor case studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00