Identification of miR-1 and miR-499 in chronic atrial fibrillation by bioinformatics analysis and experimental validation
This study provides a better understanding of the alterations in miRNA-1 and miR-499 in chronic AF from the perspective of the miRNA-mRNA network and corroborates findings through experimental validation. These findings may offer novel potential therapeutic targets for AF in the future.
Authors
- Saizhe Liu
- Yutang Wang (ORCID: https://orcid.org/0000-0002-6264-6443)
- Zhaoliang Shan
- He Meng (ORCID: https://orcid.org/0000-0002-3374-2241)
- Guiying Chen (ORCID: https://orcid.org/0000-0001-8374-6956)
- Xinpei Chen
- Yinuo Xie
- Yongjiang Ma
- Ying Liu (ORCID: https://orcid.org/0000-0002-6540-0473)
- Yu Zhang (ORCID: https://orcid.org/0000-0003-3474-422X)
- Zhuo Liang
- Hongyang Guo (ORCID: https://orcid.org/0000-0002-7089-5298)
- Jian Li (ORCID: https://orcid.org/0000-0003-2015-697X)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Kunming Medical University (CN)
- Chinese PLA General Hospital (CN)
- Beijing Anzhen Hospital (CN)
- Tianjin Chest Hospital (CN)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2024-08-16
- DOI
- https://doi.org/10.3389/fcvm.2024.1400643
- Citations
- 5
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.01