Pairing transcutaneous vagus nerve stimulation with an intensive bimanual training in children and adolescents with cerebral palsy: study protocol of a randomized sham-controlled trial
The results of this trial will assess whether tVNS can effectively boost the effects of an intensive two-week bimanual training, in improving manual dexterity in children and adolescents with cerebral palsy, ensuring safety and tolerability throughout the intervention period.<b>Clinical trial registration</b>: ClinicalTrials.gov, NCT06372028.
Authors
- Simona Orcesi (ORCID: https://orcid.org/0000-0001-8947-9342)
- Jessica Galli (ORCID: https://orcid.org/0000-0002-3347-7548)
- Alessandra Finisguerra (ORCID: https://orcid.org/0000-0002-1092-2936)
- Cosimo Urgesi (ORCID: https://orcid.org/0000-0003-0572-1328)
- Renato Borgatti (ORCID: https://orcid.org/0000-0001-8165-4994)
- Arianna Michelutti (ORCID: https://orcid.org/0000-0001-8959-7154)
- Verusca Gasparroni (ORCID: https://orcid.org/0000-0001-6130-0435)
- Andrea Ciricugno (ORCID: https://orcid.org/0000-0002-8974-6778)
- Zaira Cattaneo (ORCID: https://orcid.org/0000-0001-7516-7508)
- Maria Arioli (ORCID: https://orcid.org/0000-0001-5743-6743)
- Luigi Piccinini (ORCID: https://orcid.org/0000-0001-7027-6676)
- Elisa Fazzi (ORCID: https://orcid.org/0000-0002-2433-5927)
- Cristina Maghini (ORCID: https://orcid.org/0000-0003-1668-7954)
- Alessandra Morandi
- Viola Oldrati (ORCID: https://orcid.org/0000-0001-7179-8767)
Institutions
- University of Bergamo (IT)
- University of Udine (IT)
- University of Pavia (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- IRCCS Eugenio Medea (IT)
- University of Brescia (IT)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-08-16
- DOI
- https://doi.org/10.3389/fneur.2024.1441128
- Citations
- 4
- Primary Topic
- Cerebral Palsy and Movement Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.54
Funders
- Ministero della Salute
- Regione Lombardia
- Fondazione Regionale per la Ricerca Biomedica