Bitongqing Attenuates CIA Rats by Suppressing Macrophage Pyroptosis and Modulating the NLRP3/Caspase-1/GSDMD Pathway
The therapeutic potential of BTQ in CIA lies in its ability to inhibit NLRP3-mediated macrophage pyroptosis, thereby suggesting a promising strategy for the treatment of RA.
Authors
- Zishan Wang (ORCID: https://orcid.org/0000-0002-5980-4711)
- Yun Lü (ORCID: https://orcid.org/0000-0003-2044-2511)
- Wen Zhu (ORCID: https://orcid.org/0000-0003-3190-0071)
- Chenxi Liu (ORCID: https://orcid.org/0000-0001-8910-636X)
- Jie Pan (ORCID: https://orcid.org/0000-0001-7817-0198)
- Yunxia Wu (ORCID: https://orcid.org/0009-0009-7181-5497)
- Yue Wang (ORCID: https://orcid.org/0000-0002-0564-3019)
- Yabei Wang
- Yue Zhang (ORCID: https://orcid.org/0000-0002-8439-1488)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Jiangsu Provincial Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-08-01
- DOI
- https://doi.org/10.2147/jir.s466624
- Citations
- 6
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China