Sexually dimorphic DNA methylation and gene expression patterns in human first trimester placenta
Overall, sex dimorphic differential methylation with associated differential gene expression in the first trimester placenta is small, but there remain significant genes that may be regulated through methylation leading to differences in the first trimester placenta.
Authors
- Margareta D. Pisarska (ORCID: https://orcid.org/0000-0003-1096-6506)
- Mark O. Goodarzi (ORCID: https://orcid.org/0000-0001-6364-5103)
- Kent D. Taylor (ORCID: https://orcid.org/0000-0002-2756-4370)
- Caroline A. Jefferies (ORCID: https://orcid.org/0000-0002-8879-6722)
- Allynson Novoa
- Jinrui Cui
- Jerome I. Rotter (ORCID: https://orcid.org/0000-0001-7191-1723)
- Tania L Gonzalez (ORCID: https://orcid.org/0000-0003-3825-8544)
- Bryn E. Willson (ORCID: https://orcid.org/0000-0002-0505-2112)
- Kate Lawrenson (ORCID: https://orcid.org/0000-0002-6469-2515)
- Erica T. Wang (ORCID: https://orcid.org/0000-0002-4750-8018)
- Yii‐Der Ida Chen (ORCID: https://orcid.org/0000-0003-1741-3517)
- Akhila Swarna
- John Williams (ORCID: https://orcid.org/0000-0002-5886-0578)
- Gianna J. Zeno
- Juanita C. Ortiz
Institutions
- Cedars-Sinai Medical Center (US)
- University of California, Los Angeles (US)
- UCLA Medical Center (US)
- Harbor–UCLA Medical Center (US)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1186/s13293-024-00629-9
- Citations
- 5
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.91
Funders
- National Heart, Lung, and Blood Institute
- National Institute of Allergy and Infectious Diseases
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute of Biomedical Imaging and Bioengineering
- National Center for Advancing Translational Sciences
- Eunice Kennedy Shriver National Institute of Child Health and Human Development