Rare case of complete gonadal dysgenesis in a female patient with primary amenorrhea and a 46XY karyotype
A 16-year-old girl with absent menstruation and short stature. Further examination revealed constitutional stunting and primary amenorrhea. Karyotyping revealed a 46, XY chromosomal abnormality, whereas pelvic ultrasonography showed uterine hypoplasia and a unicornuate uterus with a rudimentary horn. After 11 months of therapy, she experienced menarche and improved secondary sexual characteristics.
Authors
- Yethindra Vityala (ORCID: https://orcid.org/0000-0003-1007-2422)
- Elmira Mamytova (ORCID: https://orcid.org/0000-0002-4322-5555)
- Tugolbai Tagaev (ORCID: https://orcid.org/0000-0002-3102-6524)
- Ulbolsun Nurbekova
- Nurbek Monolov (ORCID: https://orcid.org/0000-0001-7589-5820)
- Abdurashid Unusov
- Meerim Osmonova
- Meerim Makambaeva
Institutions
- Kyrgyz State Medical Academy (KG)
- Bishkek Humanities University (KG)
- Kyrgyz Economic University (KG)
- International University of Kyrgyzstan (KG)
- National Center of Cardiology and Internal Medicine (KG)
- International Higher School of Medicine
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1002/ccr3.9318
- Citations
- 1
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.23