Blood-based biomarkers of neuronal and glial injury in active major neuropsychiatric systemic lupus erythematosus
Blood NfL and GFAP levels are elevated in persons with SLE with active major NPSLE compared to disease matched controls and may lower after immunotherapy initiation. Larger and longitudinal studies are needed to ascertain their utility in a clinical setting.
Authors
- Ekemini A. Ogbu (ORCID: https://orcid.org/0000-0003-2126-1587)
- Ryan Kammeyer (ORCID: https://orcid.org/0000-0001-8657-3106)
- Jeffrey L. Bennett (ORCID: https://orcid.org/0000-0002-3346-1394)
- Elena W.Y. Hsieh (ORCID: https://orcid.org/0000-0003-3969-6597)
- Jennifer C. Cooper (ORCID: https://orcid.org/0000-0002-7673-6562)
- Tyler L. Borko (ORCID: https://orcid.org/0000-0002-6679-1867)
- JoAnn Zell
- Kavita V. Nair (ORCID: https://orcid.org/0009-0009-0201-1495)
- Anna Furniss (ORCID: https://orcid.org/0000-0001-5498-607X)
- Amanda L. Piquet (ORCID: https://orcid.org/0000-0001-7349-6455)
- Robert C. Fuhlbrigge (ORCID: https://orcid.org/0000-0002-0911-9310)
- Susan A. Boackle
- Kimberly Chapman
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Rheumatology Consultants (US)
- University of Cincinnati Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Lupus
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1177/09612033241272961
- Citations
- 13
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 6.11
Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases