Diagnostic and prognostic potential of the intra-tumoral microbiota profile in HPV-independent endocervical adenocarcinoma
The study reveals distinct microbial signatures in HPVI ECA, which have potential as biomarkers for disease prognosis. The correlation between these tumor-associated microbiota features and clinicopathological characteristics underscores the possibility of microbiome-based interventions. Our research provides a foundation for more in-depth studies into the cervical microbiome's role in HPVI ECA.
Authors
- Wanrun Lin (ORCID: https://orcid.org/0000-0003-0457-0097)
- Feng Zhou (ORCID: https://orcid.org/0000-0002-2402-4774)
- Wenxin Zheng (ORCID: https://orcid.org/0000-0002-4284-2893)
- Lili Chen (ORCID: https://orcid.org/0000-0003-1195-4347)
- Huijuan Zhang (ORCID: https://orcid.org/0000-0001-8883-0997)
- Xin Zhou (ORCID: https://orcid.org/0000-0001-5123-9183)
Institutions
- National Institutes of Health (US)
- Shanghai Jiao Tong University (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Women's Hospital, School of Medicine, Zhejiang University (CN)
- National Cancer Institute (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2024-08-16
- DOI
- https://doi.org/10.3389/fcimb.2024.1440017
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.94