A rare cutaneous infection with <i>Mycobacterium chelonae</i> in a pediatric patient treated with trametinib for <i>KRAS</i>‐mutated diffuse glioma
Mitogen-activated extracellular signal-regulated kinase inhibitors (MEKi) represent a promising new therapy for pediatric patients with low-grade gliomas, which frequently have abnormal signaling within the mitogen-activated protein kinase (MAP kinase) pathway. However, understanding of long-term efficacy and toxicity is limited in pediatric glioma patients. This article describes a rare presentation of a widespread cutaneous infection with Mycobacterium chelonae in a pediatric patient with a low-grade glioma treated with trametinib.
Authors
- Julianne A. Mann (ORCID: https://orcid.org/0000-0001-7781-625X)
- Nicole C. Pace
- Angel Moore
- Shabnam Momtahen (ORCID: https://orcid.org/0000-0002-8403-7585)
- Angela Ricci (ORCID: https://orcid.org/0000-0003-3507-9946)
- Matthew J. Davis (ORCID: https://orcid.org/0000-0002-3410-7100)
- Chenin Ryan
- Elizabeth A. Talbot
- Caitlin Yazel
Institutions
- Dartmouth College (US)
- Dartmouth–Hitchcock Medical Center (US)
- Children's Hospital at Dartmouth Hitchcock (US)
Publication Details
- Journal
- Pediatric Dermatology
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1111/pde.15718
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00