A rare cutaneous infection with <i>Mycobacterium chelonae</i> in a pediatric patient treated with trametinib for <i>KRAS</i>‐mutated diffuse glioma

Mitogen-activated extracellular signal-regulated kinase inhibitors (MEKi) represent a promising new therapy for pediatric patients with low-grade gliomas, which frequently have abnormal signaling within the mitogen-activated protein kinase (MAP kinase) pathway. However, understanding of long-term efficacy and toxicity is limited in pediatric glioma patients. This article describes a rare presentation of a widespread cutaneous infection with Mycobacterium chelonae in a pediatric patient with a low-grade glioma treated with trametinib.

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Publication Details

Journal
Pediatric Dermatology
Published
2024-08-15
DOI
https://doi.org/10.1111/pde.15718
Primary Topic
Mycobacterium research and diagnosis
Type
article
Field-Weighted Citation Impact
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article

A rare cutaneous infection with Mycobacterium chelonae in a pediatric patient treated with trametinib for KRAS‐mutated diffuse glioma

Julianne A. Mann, Nicole C. Pace, Angel Moore, Shabnam Momtahen et al.
Pediatric Dermatology
Mycobacterium research and diagnosis
article

A rare cutaneous infection with Mycobacterium chelonae in a pediatric patient treated with trametinib for KRAS‐mutated diffuse glioma

Julianne A. Mann, Nicole C. Pace, Angel Moore, Shabnam Momtahen, Angela Ricci, Matthew J. Davis, Chenin Ryan, Elizabeth A. Talbot, Caitlin Yazel
article en

Abstract

Mitogen-activated extracellular signal-regulated kinase inhibitors (MEKi) represent a promising new therapy for pediatric patients with low-grade gliomas, which frequently have abnormal signaling within the mitogen-activated protein kinase (MAP kinase) pathway. However, understanding of long-term efficacy and toxicity is limited in pediatric glioma patients. This article describes a rare presentation of a widespread cutaneous infection with Mycobacterium chelonae in a pediatric patient with a low-grade glioma treated with trametinib.

Pediatric DermatologyVol. 42(1)
Dartmouth College (US), Dartmouth–Hitchcock Medical Center (US), Children's Hospital at Dartmouth Hitchcock (US)
Openalex Percentile: Top 79%
Mycobacterium research and diagnosis
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