Comparative effectiveness analysis of survival with first-line palbociclib or ribociclib plus AI in HR + /HER2- advanced breast cancer (CEPRA study): preliminary analysis of real-world data from Thailand

This preliminary analysis of a real-world study demonstrated the comparable effectiveness of ribociclib and palbociclib with AI as an initial therapy for HR + /HER2 - ABC. No statistically significant difference in PFS, OS, and TTC was found in patients treated with AI combined with palbociclib or ribociclib. Longer follow-up and further prospective randomized head-to-head studies are warranted.

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Publication Details

Journal
BMC Cancer
Published
2024-08-16
DOI
https://doi.org/10.1186/s12885-024-12765-x
Citations
8
Primary Topic
Advanced Breast Cancer Therapies
Type
article
Field-Weighted Citation Impact
3.35

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article

Comparative effectiveness analysis of survival with first-line palbociclib or ribociclib plus AI in HR + /HER2- advanced breast cancer (CEPRA study): preliminary analysis of real-world data from Thailand

Napa Parinyanitikul, Archara Supavavej, Concord Wongkraisri, Suthinee Ithimakin et al.
8 citations
BMC Cancer
Advanced Breast Cancer Therapies
3.35
article

Comparative effectiveness analysis of survival with first-line palbociclib or ribociclib plus AI in HR + /HER2- advanced breast cancer (CEPRA study): preliminary analysis of real-world data from Thailand

Napa Parinyanitikul, Archara Supavavej, Concord Wongkraisri, Suthinee Ithimakin, Thitiya Dejthevaporn, Sunee Neesanun, Arunee Dechaphunkul, Patrapim Sunpaweravong, Thanate Dajsakdipon, Charuwan Akewanlop, Thiti Susiriwatananont
article en
8 citations

Abstract

This preliminary analysis of a real-world study demonstrated the comparable effectiveness of ribociclib and palbociclib with AI as an initial therapy for HR + /HER2 - ABC. No statistically significant difference in PFS, OS, and TTC was found in patients treated with AI combined with palbociclib or ribociclib. Longer follow-up and further prospective randomized head-to-head studies are warranted.

BMC CancerVol. 24(1)
Prince of Songkla University (TH), Siriraj Hospital (TH), Chulalongkorn University (TH), Mahidol University (TH), King Chulalongkorn Memorial Hospital (TH), Chulabhorn Hospital (TH), Ramathibodi Hospital (TH), Charoenkrung Pracharak Hospital (TH)
Mahidol University, Faculty of Medicine Siriraj Hospital, Mahidol University
Good health and well-being
Openalex Percentile: Top 7%
Advanced Breast Cancer Therapies
3.35
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Comparative effectiveness analysis of survival with first-line palbociclib or ribociclib plus AI in HR + /HER2- advanced breast cancer (CEPRA study): preliminary analysis of real-world data from Thailand — Napa Parinyanitikul, Archara Supavavej, et al. · BMC Cancer (2024) | TGRS Research Map | TGRS