Efficacy of non-invasive chromosome screening, preimplantation genetic testing for aneuploidy, and morphological grading in selecting embryos of patients with advanced maternal age: a three-armed prospective cohort study
In women 35-40 years old, the CLBR can be increased by selecting euploid embryos using NICS and TE-PGT. For elderly women at high risk of embryonic aneuploidy, NICS, characterized by its safety and non-invasive nature, may emerge as an alternative option for preimplantation genetic testing.
Authors
- Qin Sun
- Sijia Lü (ORCID: https://orcid.org/0000-0003-2469-1996)
- Bing Yao (ORCID: https://orcid.org/0000-0002-6657-2760)
- Dunmei Zhao
- Li Chen (ORCID: https://orcid.org/0009-0007-6683-0102)
- Juanjuan Xu
- Yaxin Yao
- Xuan Huang
Institutions
- Nanjing General Hospital of Nanjing Military Command (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Eiken Chemical (Japan) (JP)
- Sinotech Genomics (China) (CN)
- Southern Medical University (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1186/s12884-024-06736-0
- Citations
- 6
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 6.66
Funders
- Jiangsu Commission of Health
- National Natural Science Foundation of China
- Government of Jiangsu Province