Identifying clinically relevant agranulocytosis in people registered on the UK clozapine Central Non-Rechallenge Database: retrospective cohort study
Threshold-based definition of agranulocytosis may over-diagnose CIA. Monitoring schemes should take into consideration neutrophil patterns to correctly identify clinically relevant CIA. In marked contrast to previous studies, CIA occurred least in Black individuals and most in White individuals.
Authors
- David Taylor (ORCID: https://orcid.org/0000-0002-2557-1710)
- Christian Bachmann (ORCID: https://orcid.org/0000-0001-7526-2660)
- Ebenezer Oloyede (ORCID: https://orcid.org/0000-0003-1352-4017)
- Olubanké Dzahini (ORCID: https://orcid.org/0000-0003-3878-2143)
- Eromona Whiskey (ORCID: https://orcid.org/0000-0002-6146-0073)
- Kalliopi Vallianatu
- Burkhardt Funk
- Juan Miguel Lopez Alcaraz
- Shaurya Dev Singh
Institutions
- Leuphana University of Lüneburg (DE)
- Carl von Ossietzky Universität Oldenburg (DE)
- King's College London (GB)
- Universität Ulm (DE)
- Bethlem Royal Hospital (GB)
- University of Oxford (GB)
- Maudsley Hospital (GB)
Publication Details
- Journal
- The British Journal of Psychiatry
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1192/bjp.2024.104
- Citations
- 12
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.63