Active chiral flows in the separating wall during cell division

Material flow in the actomyosin cortex of a cell, during cell division, has been found to be chiral in nature. It has been attributed to active chiral torques generated in the actomyosin cortex. Here, we explore the possible signature of such chirality during the growth of the intra-cellular membrane partition, which physically divides the cell into two compartments. We use standard hydrodynamic theory of active gel to predict possible chiral flow structures in the growing partition. While the flows in the growing annular-shaped membrane partition is believed to be radial, it can also develop non-zero azimuthal velocity components (rotation) due to chirality. We show that the direction of rotation (clock or anti-clockwise) will not solely be decided by the sign of the active chiral torque but also by the relative strengths of rotational viscosity and flow coupling parameter.

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Publication Details

Journal
The Journal of Chemical Physics
Published
2024-08-16
DOI
https://doi.org/10.1063/5.0191041
Primary Topic
Micro and Nano Robotics
Type
article
Field-Weighted Citation Impact
0.00

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article

Active chiral flows in the separating wall during cell division

Anirban Sain, Mainak Chatterjee, Vijit Ganguly
The Journal of Chemical Physics
Micro and Nano Robotics
article

Active chiral flows in the separating wall during cell division

Anirban Sain, Mainak Chatterjee, Vijit Ganguly
article en

Abstract

Material flow in the actomyosin cortex of a cell, during cell division, has been found to be chiral in nature. It has been attributed to active chiral torques generated in the actomyosin cortex. Here, we explore the possible signature of such chirality during the growth of the intra-cellular membrane partition, which physically divides the cell into two compartments. We use standard hydrodynamic theory of active gel to predict possible chiral flow structures in the growing partition. While the flows in the growing annular-shaped membrane partition is believed to be radial, it can also develop non-zero azimuthal velocity components (rotation) due to chirality. We show that the direction of rotation (clock or anti-clockwise) will not solely be decided by the sign of the active chiral torque but also by the relative strengths of rotational viscosity and flow coupling parameter.

The Journal of Chemical PhysicsVol. 161(7)
Indian Institute of Technology Bombay (IN)
Science and Engineering Research Board
Openalex Percentile: Top 92%
Micro and Nano Robotics
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Active chiral flows in the separating wall during cell division — Anirban Sain, Mainak Chatterjee, et al. · The Journal of Chemical Physics (2024) | TGRS Research Map | TGRS