Tumor-derived exosome PPP3CB induce gemcitabine resistance by regulating miR-298/STAT3 in pancreatic cancer
PC cell-derived exosome PPP3CB enhances STAT3 expression by downregulating miR-298, stimulating cell growth, and suppressing cell death, thereby increasing the resistance of PC cells to GEM.
Authors
- Yong Qin (ORCID: https://orcid.org/0000-0003-3434-5747)
- Shengqian Xu
- Chaojun Wang
Institutions
- Lishui University (CN)
- Lishui Central Hospital (CN)
- Lishui City People's Hospital (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e36434
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Basic Scientific Foundation of Guangxi Institute of Public Welfare Scientific Research
- Basic Public Welfare Research Program of Zhejiang Province