5 Neuroprotective effects of metformin in diabetic peripheral neuropathy
risk phenotype for MOGAD, although one was diagnosed with a likely parainfectious myelitis and another as transverse myelitis associated with Sjogren's syndrome.Conclusion A CSF-restricted MOG-IgG profile is rare, with over half of these patients having an alternate non-MOGAD diagnosis confirmed.We strongly recommend the use of serum as the biospecimen of preference in testing for MOG IgG.We additionally urge caution in the interpretation of CSFrestricted MOG-IgG in unselected patients who do not have clinical, radiological or ancillary investigations consistent with MOGAD.
Authors
- Tushar Issar (ORCID: https://orcid.org/0000-0002-8323-6048)
- Leon Wang
- Arun V. Krishnan (ORCID: https://orcid.org/0000-0001-8883-8825)
- Natalie Kwai (ORCID: https://orcid.org/0000-0003-2934-570X)
- Roshan Dhanapalaratnam
- Ann M. Poynten (ORCID: https://orcid.org/0000-0002-4373-6881)
- Kerry–Lee Milner
- Darren Tran
Institutions
- University of Wollongong (AU)
- UNSW Sydney (AU)
- Prince of Wales Hospital (AU)
Publication Details
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1136/bmjno-2024-anzan.5
- Primary Topic
- Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00