5 Neuroprotective effects of metformin in diabetic peripheral neuropathy

risk phenotype for MOGAD, although one was diagnosed with a likely parainfectious myelitis and another as transverse myelitis associated with Sjogren's syndrome.Conclusion A CSF-restricted MOG-IgG profile is rare, with over half of these patients having an alternate non-MOGAD diagnosis confirmed.We strongly recommend the use of serum as the biospecimen of preference in testing for MOG IgG.We additionally urge caution in the interpretation of CSFrestricted MOG-IgG in unselected patients who do not have clinical, radiological or ancillary investigations consistent with MOGAD.

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Published
2024-08-01
DOI
https://doi.org/10.1136/bmjno-2024-anzan.5
Primary Topic
Neurological Disorders and Treatments
Type
article
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article

5 Neuroprotective effects of metformin in diabetic peripheral neuropathy

Tushar Issar, Leon Wang, Arun V. Krishnan, Natalie Kwai et al.
Neurological Disorders and Treatments
article

5 Neuroprotective effects of metformin in diabetic peripheral neuropathy

Tushar Issar, Leon Wang, Arun V. Krishnan, Natalie Kwai, Roshan Dhanapalaratnam, Ann M. Poynten, Kerry–Lee Milner, Darren Tran
article en

Abstract

risk phenotype for MOGAD, although one was diagnosed with a likely parainfectious myelitis and another as transverse myelitis associated with Sjogren's syndrome.Conclusion A CSF-restricted MOG-IgG profile is rare, with over half of these patients having an alternate non-MOGAD diagnosis confirmed.We strongly recommend the use of serum as the biospecimen of preference in testing for MOG IgG.We additionally urge caution in the interpretation of CSFrestricted MOG-IgG in unselected patients who do not have clinical, radiological or ancillary investigations consistent with MOGAD.

University of Wollongong (AU), UNSW Sydney (AU), Prince of Wales Hospital (AU)
Zero hunger
Openalex Percentile: Top 85%
Neurological Disorders and Treatments
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5 Neuroprotective effects of metformin in diabetic peripheral neuropathy — Tushar Issar, Leon Wang, et al. · (2024) | TGRS Research Map | TGRS