Identification of Genetic Variants in Progressive Supranuclear Palsy in Southeast Asia
The genetic findings in our PSP cohorts appear to be somewhat distinct from those in Western populations, and also suggest an overlap of the genetic architecture between PSP and other neurodegenerative diseases. Further functional studies and validation in independent Asian cohorts will be useful for improving our understanding of PSP genetics and guiding genetic screening strategies in these populations. © 2024 International Parkinson and Movement Disorder Society.
Authors
- Shanthi Viswanathan (ORCID: https://orcid.org/0000-0002-0094-0540)
- Yi Jayne Tan (ORCID: https://orcid.org/0000-0003-1486-4734)
- Jia Nee Foo (ORCID: https://orcid.org/0000-0001-9899-2308)
- Adeline Su Lyn Ng (ORCID: https://orcid.org/0000-0001-8822-8496)
- Eng‐King Tan (ORCID: https://orcid.org/0000-0003-2977-9743)
- Shen‐Yang Lim (ORCID: https://orcid.org/0000-0002-6942-2522)
- Yuen Kang Chia (ORCID: https://orcid.org/0000-0001-9395-3107)
- Jia Lun Lim (ORCID: https://orcid.org/0000-0003-4485-7674)
- Michelle Mulan Lian (ORCID: https://orcid.org/0000-0001-6881-2660)
- Ai Huey Tan (ORCID: https://orcid.org/0000-0002-2979-3839)
- Weng Khong Lim (ORCID: https://orcid.org/0000-0003-4391-1130)
- Alfand Marl F. Dy Closas (ORCID: https://orcid.org/0000-0003-1209-9573)
- Azlina Ahmad‐Annuar (ORCID: https://orcid.org/0000-0001-6329-4366)
Institutions
- Agency for Science, Technology and Research (SG)
- SingHealth (SG)
- Nanyang Technological University (SG)
- Hospital Kuala Lumpur (MY)
- Davao Doctors Hospital (PH)
- University of Malaya (MY)
- SingHealth Duke-NUS Academic Medical Centre (SG)
- Duke-NUS Medical School (SG)
- National Neuroscience Institute (SG)
- Queen Elizabeth Hospital (MY)
- Genome Institute of Singapore (SG)
Publication Details
- Journal
- Movement Disorders
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1002/mds.29932
- Citations
- 6
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.21
Funders
- Universiti Malaya
- Ministry of Education, India
- Bộ Giáo dục và Ðào tạo
- Medical Research Council
- National Medical Research Council