Intestinal microbiology and urinary tract infection associated risk in long-term aged care residents
No association between the gut microbiome and UTI incidence, as has been reported in younger individuals, is evident in long-term aged care residents. Considerable variability in gut microbiome characteristics, relating to high antibiotic exposure and age-related physiological and immunological factors, could mask such a relationship. However, it cannot be discounted that increased UTI risk in the elderly is independent of microbiome-mediated mechanisms.
Authors
- Erin Flynn (ORCID: https://orcid.org/0000-0002-7107-7641)
- Lito E. Papanicolas (ORCID: https://orcid.org/0000-0002-5838-7274)
- Andrew P. Shoubridge (ORCID: https://orcid.org/0000-0002-5148-4063)
- Maria Crotty (ORCID: https://orcid.org/0000-0002-2996-5135)
- David Gordon (ORCID: https://orcid.org/0000-0003-3276-9685)
- Jocelyn M. Choo (ORCID: https://orcid.org/0000-0001-9500-8360)
- Sophie Miller (ORCID: https://orcid.org/0009-0003-3889-7941)
- Craig Whitehead (ORCID: https://orcid.org/0000-0001-5859-8314)
- Lucy Carpenter
- Miriam A. Lynn (ORCID: https://orcid.org/0000-0003-4300-1380)
- Lex E. X. Leong (ORCID: https://orcid.org/0000-0002-5073-2272)
- Steven Taylor (ORCID: https://orcid.org/0000-0003-4357-8243)
- Maria C. Inacio (ORCID: https://orcid.org/0000-0001-8261-2665)
- Steve Wesselingh (ORCID: https://orcid.org/0000-0001-5605-1147)
- Geraint B. Rogers (ORCID: https://orcid.org/0000-0003-4054-1947)
Institutions
- South Australia Pathology (AU)
- Flinders University (AU)
- University of South Australia (AU)
- Flinders Medical Centre (AU)
- SA Health (AU)
- Adelaide Institute for Sleep Health (AU)
- South Australian Health and Medical Research Institute (AU)
Publication Details
- Journal
- Communications Medicine
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1038/s43856-024-00583-y
- Citations
- 9
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 3.48
Funders
- Hospital Research Foundation
- EMBL Australia
- Medical Research Council
- National Health and Medical Research Council