Expanding treatment options for patients with HER2+ metastatic breast cancer with margetuximab plus chemotherapy: a case report series

Clinical outcomes from three heavily pretreated patients with metastatic HER2+/HR+ MBC demonstrated that margetuximab plus chemotherapy resulted in real-world PFS comparable to that reported in the controlled pivotal clinical trial and support use of this targeted therapy option in appropriately identified patients.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-08-16
DOI
https://doi.org/10.3389/fonc.2024.1419246
Citations
1
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.28

Funders

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article

Expanding treatment options for patients with HER2+ metastatic breast cancer with margetuximab plus chemotherapy: a case report series

Reshma Mahtani, Iuliia Kovalenko, Kristen L. Phiel, Natasha Harpalani et al.
1 citations
Frontiers in Oncology
HER2/EGFR in Cancer Research
0.28
article

Expanding treatment options for patients with HER2+ metastatic breast cancer with margetuximab plus chemotherapy: a case report series

Reshma Mahtani, Iuliia Kovalenko, Kristen L. Phiel, Natasha Harpalani, Fengting Yan
article en
1 citations

Abstract

Clinical outcomes from three heavily pretreated patients with metastatic HER2+/HR+ MBC demonstrated that margetuximab plus chemotherapy resulted in real-world PFS comparable to that reported in the controlled pivotal clinical trial and support use of this targeted therapy option in appropriately identified patients.

Frontiers in OncologyVol. 14
Baptist Hospital of Miami (US), Memorial Sloan Kettering Cancer Center (US), Swedish Medical Center (US), Baptist Health South Florida (US), University of Pittsburgh Medical Center (US)
MacroGenics
Good health and well-being
Openalex Percentile: Top 37%
HER2/EGFR in Cancer Research
0.28
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Expanding treatment options for patients with HER2+ metastatic breast cancer with margetuximab plus chemotherapy: a case report series — Reshma Mahtani, Iuliia Kovalenko, et al. · Frontiers in Oncology (2024) | TGRS Research Map | TGRS