Combined Effects of Nasal Ketamine and Trauma-Focused Psychotherapy in Treatment-Resistant Post-Traumatic Stress Disorder: A Pilot Case Series

Despite potential variations in clinical profiles among the patients, the therapy program demonstrated positive outcomes for all participants. Nasally administered ketamine was well tolerated and resulted in immediate symptom reduction in tension, anxiety, and common PTSD symptoms. However, to validate these findings and compare treatment efficacy, future randomized controlled trials are warranted, especially in comparison with trauma-focused therapy alone.

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Publication Details

Journal
Behavioral Sciences
Published
2024-08-16
DOI
https://doi.org/10.3390/bs14080717
Citations
6
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
2.69
Controls
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article

Combined Effects of Nasal Ketamine and Trauma-Focused Psychotherapy in Treatment-Resistant Post-Traumatic Stress Disorder: A Pilot Case Series

Stefan Vetter, Birgit Kleim, Erich Seifritz, Judith Rohde et al.
6 citations
Behavioral Sciences
Treatment of Major Depression
2.69
article

Combined Effects of Nasal Ketamine and Trauma-Focused Psychotherapy in Treatment-Resistant Post-Traumatic Stress Disorder: A Pilot Case Series

Stefan Vetter, Birgit Kleim, Erich Seifritz, Judith Rohde, Golo Kronenberg, Sebastian Olbrich, Elena Hickmann, Marco Buchmann
article en
6 citations

Abstract

Despite potential variations in clinical profiles among the patients, the therapy program demonstrated positive outcomes for all participants. Nasally administered ketamine was well tolerated and resulted in immediate symptom reduction in tension, anxiety, and common PTSD symptoms. However, to validate these findings and compare treatment efficacy, future randomized controlled trials are warranted, especially in comparison with trauma-focused therapy alone.

Behavioral SciencesVol. 14(8)
University of Zurich (CH), University Hospital of Zurich (CH)
Good health and well-being
Openalex Percentile: Top 10%
Treatment of Major Depression
2.69
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Combined Effects of Nasal Ketamine and Trauma-Focused Psychotherapy in Treatment-Resistant Post-Traumatic Stress Disorder: A Pilot Case Series — Stefan Vetter, Birgit Kleim, et al. · Behavioral Sciences (2024) | TGRS Research Map | TGRS