Synchronized Brain and Pulmonary Lesions: A Diagnostic Challenge

This case report details a 50-year-old female presenting with pulmonary and neurological symptoms initially diagnosed as disseminated tuberculosis, leading to treatment with antitubercular therapy. Despite initial improvements, daily bedside evaluations revealed a new cervical lymph node, which, upon further investigation, revealed features suggestive of malignancy. Further biopsy confirmed the diagnosis of adenocarcinoma of the lung with cerebral metastases. The patient was started on palliative chemotherapy but eventually succumbed due to complications. This case underscores the diagnostic challenge of approaching synchronous cerebral and pulmonary lesions, highlighting the critical role of thorough daily evaluations in accurate diagnosis and timely intervention. While the initial diagnosis focused on tuberculosis, the discovery of the cervical lymph node was pivotal in identifying metastatic lung adenocarcinoma. This case emphasizes the importance of considering malignancy in similar clinical scenarios and using comprehensive diagnostic approaches, including advanced imaging and timely biopsies, to ensure accurate diagnosis and appropriate management.

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Publication Details

Journal
Cureus
Published
2024-08-16
DOI
https://doi.org/10.7759/cureus.66990
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Synchronized Brain and Pulmonary Lesions: A Diagnostic Challenge

Mahendra Kumar Kalappan, Abinaya Srinivasa Rangan, Keesari Sai Sandeep Reddy, Nithesh Babu Ramesh et al.
Cureus
Brain Metastases and Treatment
article

Synchronized Brain and Pulmonary Lesions: A Diagnostic Challenge

Mahendra Kumar Kalappan, Abinaya Srinivasa Rangan, Keesari Sai Sandeep Reddy, Nithesh Babu Ramesh, V. Govindaraj
article en

Abstract

This case report details a 50-year-old female presenting with pulmonary and neurological symptoms initially diagnosed as disseminated tuberculosis, leading to treatment with antitubercular therapy. Despite initial improvements, daily bedside evaluations revealed a new cervical lymph node, which, upon further investigation, revealed features suggestive of malignancy. Further biopsy confirmed the diagnosis of adenocarcinoma of the lung with cerebral metastases. The patient was started on palliative chemotherapy but eventually succumbed due to complications. This case underscores the diagnostic challenge of approaching synchronous cerebral and pulmonary lesions, highlighting the critical role of thorough daily evaluations in accurate diagnosis and timely intervention. While the initial diagnosis focused on tuberculosis, the discovery of the cervical lymph node was pivotal in identifying metastatic lung adenocarcinoma. This case emphasizes the importance of considering malignancy in similar clinical scenarios and using comprehensive diagnostic approaches, including advanced imaging and timely biopsies, to ensure accurate diagnosis and appropriate management.

CureusVol. 16(8)
Saveetha University (IN)
Openalex Percentile: Top 76%
Brain Metastases and Treatment
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