3124 Unexpected intracerebral haemorrhage in a younger patient: a case report of probable iatrogenic cerebral amyloid angiopathy

perampanel) in addition to plasma exchange.In discussion with immunology, cyclophosphamide induction commenced.She was seizure-free on day 4 intensive care (ICU) admission.Anaesthesia and ASMs were gradually weaned.She was discharged following 41-day ICU admission and 3-month inpatient stay.She remains seizure-free 18 months since admission.Discussion Thymoma can present with paraneoplastic neurological syndromes.There is no clear evidence that anti-GAD/ anti-Hu antibodies are pathogenic in the associated syndrome.The case highlights the importance of aggressive multimodal immunotherapy in the setting of super-refractory status epilepticus of autoimmune aetiology.

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Published
2024-08-01
DOI
https://doi.org/10.1136/bmjno-2024-anzan.112
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
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article
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article

3124 Unexpected intracerebral haemorrhage in a younger patient: a case report of probable iatrogenic cerebral amyloid angiopathy

Yue Wyld
Intracerebral and Subarachnoid Hemorrhage Research
article

3124 Unexpected intracerebral haemorrhage in a younger patient: a case report of probable iatrogenic cerebral amyloid angiopathy

Yue Wyld
article en

Abstract

perampanel) in addition to plasma exchange.In discussion with immunology, cyclophosphamide induction commenced.She was seizure-free on day 4 intensive care (ICU) admission.Anaesthesia and ASMs were gradually weaned.She was discharged following 41-day ICU admission and 3-month inpatient stay.She remains seizure-free 18 months since admission.Discussion Thymoma can present with paraneoplastic neurological syndromes.There is no clear evidence that anti-GAD/ anti-Hu antibodies are pathogenic in the associated syndrome.The case highlights the importance of aggressive multimodal immunotherapy in the setting of super-refractory status epilepticus of autoimmune aetiology.

Sunshine Coast University Hospital (AU)
Openalex Percentile: Top 79%
Intracerebral and Subarachnoid Hemorrhage Research
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