Duck enteritis virus UL7 is a late gene and the UL7-encoded protein co-localizes with pUL51

Background Duck enteritis virus (DEV) belongs to Alphaherpesvirinae ; little is known about the DEV UL7 gene and its encoded protein. This study examined the molecular characteristics of DEV pUL7 in vitro and determined whether DEV pUL7 co-localizes with pUL51. Results The results showed that UL7 can be regarded as a late gene. Moreover, immunofluorescence assay revealed that pUL7 was located around the perinuclear cytoplasmic region and co-localized with pUL51 in the cytoplasm and nucleus after transfection into duck embryo fibroblast cells (DEFs). Conclusion In conclusion, we identified the molecular characteristics of the DEV UL7 gene, which is a late gene, and the co-localization of its encoded protein with pUL51 in transfected DEFs, enriching our understanding of pUL7 and future research directions.

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Publication Details

Journal
Acta Virologica
Published
2024-08-16
DOI
https://doi.org/10.3389/av.2024.12023
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Duck enteritis virus UL7 is a late gene and the UL7-encoded protein co-localizes with pUL51

Juan Huang, Mafeng Liu, Sai Mao, Ying Wu et al.
Acta Virologica
Herpesvirus Infections and Treatments
article

Duck enteritis virus UL7 is a late gene and the UL7-encoded protein co-localizes with pUL51

Juan Huang, Mafeng Liu, Sai Mao, Ying Wu, Jie Huang, Shaqiu Zhang, Renyong Jia, Xuming Ou, Qun Gao, Dekang Zhu, Shun Chen, Bin Tian, Mingshu Wang, Qiao Yang, Anchun Cheng, Di Sun, Xinxin Zhao
article en

Abstract

Background Duck enteritis virus (DEV) belongs to Alphaherpesvirinae ; little is known about the DEV UL7 gene and its encoded protein. This study examined the molecular characteristics of DEV pUL7 in vitro and determined whether DEV pUL7 co-localizes with pUL51. Results The results showed that UL7 can be regarded as a late gene. Moreover, immunofluorescence assay revealed that pUL7 was located around the perinuclear cytoplasmic region and co-localized with pUL51 in the cytoplasm and nucleus after transfection into duck embryo fibroblast cells (DEFs). Conclusion In conclusion, we identified the molecular characteristics of the DEV UL7 gene, which is a late gene, and the co-localization of its encoded protein with pUL51 in transfected DEFs, enriching our understanding of pUL7 and future research directions.

Acta VirologicaVol. 68
China Agricultural Research System
Openalex Percentile: Top 79%
Herpesvirus Infections and Treatments
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Duck enteritis virus UL7 is a late gene and the UL7-encoded protein co-localizes with pUL51 — Juan Huang, Mafeng Liu, et al. · Acta Virologica (2024) | TGRS Research Map | TGRS