Identification and Mendelian randomization validation of pathogenic gene biomarkers in obstructive sleep apnea
Through WGCNA, this analysis uncovered significant genetic foundations of OSA, identifying 2,502 DEGs and 194 genes associated with the disorder. Among these, CETN3 and GTF2A2 were found to have causal relationships with OSA.
Authors
- Peijun Liu
- Nianjin Gong
- Yu Tuo
Institutions
- The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-08-16
- DOI
- https://doi.org/10.3389/fneur.2024.1442835
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hubei Province