Identification and Mendelian randomization validation of pathogenic gene biomarkers in obstructive sleep apnea

Through WGCNA, this analysis uncovered significant genetic foundations of OSA, identifying 2,502 DEGs and 194 genes associated with the disorder. Among these, CETN3 and GTF2A2 were found to have causal relationships with OSA.

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Publication Details

Journal
Frontiers in Neurology
Published
2024-08-16
DOI
https://doi.org/10.3389/fneur.2024.1442835
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Identification and Mendelian randomization validation of pathogenic gene biomarkers in obstructive sleep apnea

Peijun Liu, Nianjin Gong, Yu Tuo
Frontiers in Neurology
Obstructive Sleep Apnea Research
article

Identification and Mendelian randomization validation of pathogenic gene biomarkers in obstructive sleep apnea

Peijun Liu, Nianjin Gong, Yu Tuo
article en

Abstract

Through WGCNA, this analysis uncovered significant genetic foundations of OSA, identifying 2,502 DEGs and 194 genes associated with the disorder. Among these, CETN3 and GTF2A2 were found to have causal relationships with OSA.

Frontiers in NeurologyVol. 15
The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture (CN)
Natural Science Foundation of Hubei Province
Good health and well-being
Openalex Percentile: Top 82%
Obstructive Sleep Apnea Research
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Identification and Mendelian randomization validation of pathogenic gene biomarkers in obstructive sleep apnea — Peijun Liu, Nianjin Gong, et al. · Frontiers in Neurology (2024) | TGRS Research Map | TGRS