DNA methylation-estimated phenotypes, telomere length and risk of ischemic stroke: epigenetic age acceleration of screening and a Mendelian randomization study
The study provides insight into the relationship between DNAmAge and ischemic stroke, particularly cardioembolic stroke, and suggests possible gender differences. These insights carry profound clinical significance and set stage for future investigations into the entwined pathways of stroke and accelerated aging.
Authors
- Zengliang Wang (ORCID: https://orcid.org/0000-0002-8411-5678)
- Rena Abudusalamu
- Aierpati Maimaiti (ORCID: https://orcid.org/0000-0002-6876-3165)
- Chenguang Hao
- Yongxin Wang (ORCID: https://orcid.org/0000-0002-0172-9085)
- Dengfeng Han (ORCID: https://orcid.org/0009-0003-1658-4346)
- Jianhua Ma (ORCID: https://orcid.org/0009-0004-6822-4729)
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Aging
- Published
- 2024-08-16
- DOI
- https://doi.org/10.18632/aging.206072
- Citations
- 4
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Natural Science Foundation of Xinjiang Province
- Science and Technology Department of Xinjiang Uygur Autonomous Region