Long noncoding RNA NONHSAT122636.2 attenuates myocardial inflammation and apoptosis in myocarditis
NONHSAT122636.2 attenuates myocardial inflammation and apoptosis in myocarditis. Additionally, its expression decreases in the peripheral blood of children suffering from myocarditis and in patients who are diagnosed for the first time showing higher diagnostic sensitivity and specificity. This decrease is negatively correlated with the degree of inflammation. Overall, the study suggests that NONHSAT122636.2 can be exploited as a potential diagnostic biomarker for pediatric myocarditis.
Authors
- Yongjiao Liu
- Bo Han (ORCID: https://orcid.org/0000-0001-9501-8702)
- Hailin Jia (ORCID: https://orcid.org/0000-0002-4051-1089)
- Jing Wang (ORCID: https://orcid.org/0000-0002-3773-1005)
- Mengjie Ma (ORCID: https://orcid.org/0000-0001-8450-3286)
- Xinxin Feng (ORCID: https://orcid.org/0000-0002-1879-0253)
- Li Zhang (ORCID: https://orcid.org/0000-0002-4702-9658)
Institutions
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1371/journal.pone.0307779
- Citations
- 3
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- National Natural Science Foundation of China