An FPGA-Based 64-Channel Readout Electronics for High-Resolution TOF-PET Detectors

Field programmable logic array (FPGA)-based readout electronics has shown its capability of channel-by-channel signal readout for time-of-flight positron emission tomography (TOF-PET) detectors. However, for detectors that rely on light sharing to achieve subpixel resolution, the high-linear measurement dynamic range of the readout electronics is highly required. In this article, the problems with dynamic range in our previously proposed FPGA-based fast linear discharge circuit are investigated and corresponding methods are proposed to enhance its small signal measurement capability and improve the timing performance as well. A practical 64-channel TOF-PET detector module was constructed and evaluated. The readout electronics test results demonstrated a 240x measurement dynamic range with 99.5% conversion linearity. In the case that the <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$8\times 8$ </tex-math></inline-formula> silicon photomultiplier (SiPM) array in the detector combines with an <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$8\times 8$ </tex-math></inline-formula> LYSO crystal (each <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$3.2\times 3.2\times 10$ </tex-math></inline-formula> mm3) array, the average energy and coincidence time resolution of the detector are measured as 10.68% (511 keV) and 364.9 ps, respectively. To demonstrate the benefit of large dynamic range to high-resolution detectors, the crystal array in the detector was replaced by a <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$24\times 24$ </tex-math></inline-formula> LYSO array (each <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$1.04\times 1.04\times 15$ </tex-math></inline-formula> mm3) and achieved 1-mm resolution. The test results confirm that the proposed FPGA-based readout circuit is practical for laboratory instrumentation

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Publication Details

Journal
IEEE Transactions on Radiation and Plasma Medical Sciences
Published
2024-08-16
DOI
https://doi.org/10.1109/trpms.2024.3443831
Citations
2
Primary Topic
Medical Imaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.81

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article

An FPGA-Based 64-Channel Readout Electronics for High-Resolution TOF-PET Detectors

Xiaoguang Kong, Xiang Zhang, M. Wang, Yonggang Wang
2 citations
IEEE Transactions on Radiation and Plasma Medical Sciences
Medical Imaging Techniques and Applications
0.81
article

An FPGA-Based 64-Channel Readout Electronics for High-Resolution TOF-PET Detectors

Xiaoguang Kong, Xiang Zhang, M. Wang, Yonggang Wang
article en
2 citations

Abstract

Field programmable logic array (FPGA)-based readout electronics has shown its capability of channel-by-channel signal readout for time-of-flight positron emission tomography (TOF-PET) detectors. However, for detectors that rely on light sharing to achieve subpixel resolution, the high-linear measurement dynamic range of the readout electronics is highly required. In this article, the problems with dynamic range in our previously proposed FPGA-based fast linear discharge circuit are investigated and corresponding methods are proposed to enhance its small signal measurement capability and improve the timing performance as well. A practical 64-channel TOF-PET detector module was constructed and evaluated. The readout electronics test results demonstrated a 240x measurement dynamic range with 99.5% conversion linearity. In the case that the <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$8\times 8$ </tex-math></inline-formula> silicon photomultiplier (SiPM) array in the detector combines with an <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$8\times 8$ </tex-math></inline-formula> LYSO crystal (each <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$3.2\times 3.2\times 10$ </tex-math></inline-formula> mm3) array, the average energy and coincidence time resolution of the detector are measured as 10.68% (511 keV) and 364.9 ps, respectively. To demonstrate the benefit of large dynamic range to high-resolution detectors, the crystal array in the detector was replaced by a <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$24\times 24$ </tex-math></inline-formula> LYSO array (each <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$1.04\times 1.04\times 15$ </tex-math></inline-formula> mm3) and achieved 1-mm resolution. The test results confirm that the proposed FPGA-based readout circuit is practical for laboratory instrumentation

IEEE Transactions on Radiation and Plasma Medical SciencesVol. 9(1)
University of Science and Technology of China (CN), Hefei University (CN)
National Natural Science Foundation of China
Affordable and clean energy
Openalex Percentile: Top 26%
Medical Imaging Techniques and Applications
0.81
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