Research and application of SPR sensor membrane layer structure improvement

In this study, by redesigning the membrane layer structure of the traditional Kretschmann model of the surface plasmon resonance sensor, the problem of small measurement range of the solution concentration of the original structure and the reduced sensitivity of the sensor when measuring liquids with higher concentration was solved. In this paper, the transfer matrix method was adopted to calculate the attenuated total reflection intensity, and the surface plasmon resonance curve was obtained using the angular modulation method, and its feasibility was verified by simulation. The final experimental results show that for common transparent liquids such as NaCl solution, glucose solution, sucrose solution, etc. The membrane layer structure proposed in this paper can expand the originally small concentration measurement range to a full concentration range measurement, which is very effective for expanding the measurement range.