Characterization of Digestive Manifestations in Patients with Impaired PTH/PTHrP Signaling Disorder/Pseudohypoparathyroidism
Our work shows for the first time that digestive manifestations, including constipation, occur frequently in children followed for iPPSD, suggesting a potential role of Gsα and G protein receptors in the digestive tract. It is well known that constipation and digestive symptoms alter quality of life. Early management is therefore essential to improve the quality of life of children followed for iPPSD. Our data need to be confirmed on a larger cohort.
Authors
- Béatrice Dubern (ORCID: https://orcid.org/0000-0002-0065-5344)
- Agnès Linglart (ORCID: https://orcid.org/0000-0003-3455-002X)
- Jugurtha Berkenou
- Christelle Audrain
- Anya Rothenbühler (ORCID: https://orcid.org/0000-0001-9246-5160)
- Bérénice Goy
Institutions
- Inserm (FR)
- Université Paris-Saclay (FR)
- Sorbonne Université (FR)
- Hôpital Armand-Trousseau (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Bicêtre Hospital (FR)
Publication Details
- Journal
- Hormone Research in Paediatrics
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1159/000539995
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 0.00