Oral Cannabis Extract for Secondary Prevention of Chemotherapy-Induced Nausea and Vomiting: Final Results of a Randomized, Placebo-Controlled, Phase II/III Trial
THC:CBD is an effective adjunct for chemotherapy-induced nausea and vomiting despite standard antiemetic prophylaxis, but was associated with additional adverse events. Drug availability, cultural attitudes, legal status, and preferences may affect implementation. Future analyses will evaluate the cost-effectiveness of THC:CBD.
Authors
- Annette Tognela (ORCID: https://orcid.org/0000-0003-0875-4352)
- Stephen Della‐Fiorentina (ORCID: https://orcid.org/0000-0003-1017-5595)
- Peter T. Fox (ORCID: https://orcid.org/0000-0002-0465-2028)
- Ganessan Kichenadasse (ORCID: https://orcid.org/0000-0001-9923-5149)
- Peter Grimison (ORCID: https://orcid.org/0000-0002-2653-1657)
- Antony Mersiades (ORCID: https://orcid.org/0000-0002-0037-3101)
- Morteza Aghmesheh (ORCID: https://orcid.org/0000-0003-1664-4743)
- Rachael L. Morton (ORCID: https://orcid.org/0000-0001-7834-0572)
- Ian Olver (ORCID: https://orcid.org/0000-0001-5478-1576)
- Martin R. Stockler (ORCID: https://orcid.org/0000-0003-3793-8724)
- Anna Walsh (ORCID: https://orcid.org/0000-0002-8920-248X)
- Gavin M. Marx (ORCID: https://orcid.org/0000-0002-1016-6544)
- Helen Wheeler (ORCID: https://orcid.org/0000-0002-6949-354X)
- Paul Haber (ORCID: https://orcid.org/0000-0001-8915-8872)
- Yvonne Lee (ORCID: https://orcid.org/0000-0002-2422-9198)
- Robert John Simes (ORCID: https://orcid.org/0000-0002-3740-7563)
- Stephen Begbie (ORCID: https://orcid.org/0000-0001-9277-6479)
- Matthew Ming Ki Chan (ORCID: https://orcid.org/0000-0001-6759-6935)
- Ehtesham Abdi (ORCID: https://orcid.org/0000-0002-0978-7183)
- Craig Gedye (ORCID: https://orcid.org/0000-0002-1629-4352)
- Jenny Shannon
- Adrienne Kirby (ORCID: https://orcid.org/0000-0003-2662-4471)
- Jasotha Sanmugarajah
- Karen Briscoe (ORCID: https://orcid.org/0000-0002-1491-6920)
Institutions
- Camden and Campbelltown Hospitals (AU)
- The University of Sydney (AU)
- Sydney Adventist Hospital (AU)
- Royal Prince Alfred Hospital (AU)
- Royal North Shore Hospital (AU)
- Gold Coast Hospital (AU)
- Gosford Hospital (AU)
- Wollongong Hospital (AU)
- Nepean Hospital (AU)
- Flinders Medical Centre (AU)
- Coffs Harbour City Council (AU)
- Tweed Shire Council (AU)
- Chris O’Brien Lifehouse (AU)
- Western NSW Local Health District (AU)
- Port Macquarie Base Hospital (AU)
- Calvary Mater Newcastle Hospital (AU)
- National Health and Medical Research Council (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1200/jco.23.01836
- Citations
- 23
- Primary Topic
- Nausea and vomiting management
- Type
- article
- Field-Weighted Citation Impact
- 13.17
Funders
- Medical Research Council
- National Health and Medical Research Council