Integrated network pharmacology and molecular docking to investigate the potential mechanism of Tufuling on Alzheimer's disease

This study preliminarily verified the combination of Tu Fu Ling's screened active ingredient and the calculated core target, suggesting a potential mechanism of action to improve the symptoms of AD patients through multi-target and multi-pathway approaches. This provides a valuable reference for further exploration of the pharmacological mechanism of AD and the formulation of drug therapy.

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Publication Details

Journal
Heliyon
Published
2024-08-01
DOI
https://doi.org/10.1016/j.heliyon.2024.e36471
Citations
7
Primary Topic
Pharmacological Effects of Natural Compounds
Type
article
Field-Weighted Citation Impact
3.27

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article

Integrated network pharmacology and molecular docking to investigate the potential mechanism of Tufuling on Alzheimer's disease

Xinpei Zhou, Bensi Zhang, Ziyou Zhang, Hao‐Yi Wu et al.
7 citations
Heliyon
Pharmacological Effects of Natural Compounds
3.27
article

Integrated network pharmacology and molecular docking to investigate the potential mechanism of Tufuling on Alzheimer's disease

Xinpei Zhou, Bensi Zhang, Ziyou Zhang, Hao‐Yi Wu, Jiamao Cheng
article en
7 citations

Abstract

This study preliminarily verified the combination of Tu Fu Ling's screened active ingredient and the calculated core target, suggesting a potential mechanism of action to improve the symptoms of AD patients through multi-target and multi-pathway approaches. This provides a valuable reference for further exploration of the pharmacological mechanism of AD and the formulation of drug therapy.

HeliyonVol. 10(16)
Dali University (CN)
Yunnan Provincial Science and Technology Department
Zero hunger
Openalex Percentile: Top 8%
Pharmacological Effects of Natural Compounds
3.27
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