Mitochondrial protein deacetylation by SIRT3 in osteoclasts promotes bone resorption with aging in female mice
Decreasing mitophagic flux in osteoclasts may be a promising pharmacotherapeutic approach to treat osteoporosis in older adults.
Authors
- Kimberly Richardson
- Nükhet Aykin‐Burns (ORCID: https://orcid.org/0000-0001-8574-4102)
- Aaron Warren (ORCID: https://orcid.org/0000-0002-0042-9021)
- Gareeballah Osman Adam (ORCID: https://orcid.org/0000-0002-8650-8117)
- Stephanie D. Byrum (ORCID: https://orcid.org/0000-0002-1783-3610)
- Maria Almeida (ORCID: https://orcid.org/0000-0002-6722-9200)
- Wen Ling
- Ha‐Neui Kim (ORCID: https://orcid.org/0000-0003-2498-6700)
- Kimberly J. Krager
- Jeff D. Thostenson (ORCID: https://orcid.org/0009-0003-9635-5729)
Institutions
- Arkansas Children's Hospital (US)
- Institute for Musculoskeletal Health (AU)
- Arkansas Children's Nutrition Center (US)
- Carolina Musculoskeletal Institute (US)
- Pharmaceutical Biotechnology (Czechia) (CZ)
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1016/j.molmet.2024.102012
- Citations
- 10
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 3.44
Funders
- National Institutes of Health