Comprehensive database of HIV mutations selected during antiretroviral in vitro passage experiments

We created a database of published ARV in vitro selection experiments. Mutations emerging from these experiments generally predict those observed in persons receiving the same ARV. However, there are notable differences in mutation frequencies between in vitro and in vivo settings.

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Publication Details

Journal
Antiviral Research
Published
2024-08-16
DOI
https://doi.org/10.1016/j.antiviral.2024.105988
Citations
5
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
1.47

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article

Comprehensive database of HIV mutations selected during antiretroviral in vitro passage experiments

Kaiming Tao, Philip L. Tzou, Pavithra Nagarajan, Robert W. Shafer et al.
5 citations
Antiviral Research
HIV Research and Treatment
1.47
article

Comprehensive database of HIV mutations selected during antiretroviral in vitro passage experiments

Kaiming Tao, Philip L. Tzou, Pavithra Nagarajan, Robert W. Shafer, Jinru Zhou
article en
5 citations

Abstract

We created a database of published ARV in vitro selection experiments. Mutations emerging from these experiments generally predict those observed in persons receiving the same ARV. However, there are notable differences in mutation frequencies between in vitro and in vivo settings.

Antiviral ResearchVol. 230
Stanford Medicine (US), Stanford University (US)
GlaxoSmithKline, Gilead Sciences, ViiV Healthcare, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 18%
HIV Research and Treatment
1.47
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