Clinical and genetic associations of asymmetric apical and septal left ventricular hypertrophy
Apical and septal mass may be driven by genes distinct from total left ventricular mass, suggesting unique genetic profiles for patterns of hypertrophy. Focal hypertrophy confers independent and additive risk to incident cardiovascular disease. Our findings emphasize the significance of characterizing distinct subtypes of left ventricular hypertrophy. Further studies are needed in multi-ethnic cohorts.
Authors
- Alan C. Kwan (ORCID: https://orcid.org/0000-0002-4393-1011)
- Miloš Vukadinovic (ORCID: https://orcid.org/0000-0002-0431-1493)
- Victoria Yuan (ORCID: https://orcid.org/0009-0007-3971-9345)
- Florian Rader (ORCID: https://orcid.org/0000-0003-1637-5096)
- David Ouyang (ORCID: https://orcid.org/0000-0002-3813-7518)
- Debiao Li (ORCID: https://orcid.org/0000-0001-8560-8231)
Institutions
- Cedars-Sinai Medical Center (US)
- University of California, Los Angeles (US)
- Samueli Institute (US)
- Cedars-Sinai Smidt Heart Institute (US)
Publication Details
- Journal
- European Heart Journal - Digital Health
- Published
- 2024-08-08
- DOI
- https://doi.org/10.1093/ehjdh/ztae060
- Citations
- 5
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Servier