Rivaroxaban for Thromboembolism Prophylaxis in Patients with Nephrotic Syndrome: A Single-Arm, Prospective Study
Hypoalbuminemia significantly affects the pharmacokinetics of rivaroxaban in NS patients. A dose-adjustment strategy based on rivaroxaban concentrations, accounting for variable albumin levels, may improve the safety and efficacy of thromboprophylaxis in this population.
Authors
- Qinxin Song (ORCID: https://orcid.org/0000-0003-3452-6396)
- Honglang Xie (ORCID: https://orcid.org/0000-0001-5248-6055)
- Qing Zhou (ORCID: https://orcid.org/0000-0002-1917-5105)
- Yuanmao Tu
- Zhi‐Chun Gu (ORCID: https://orcid.org/0000-0002-1245-9690)
- Guohua Zhou
- Wei Meng (ORCID: https://orcid.org/0000-0002-1495-7976)
- Lihua Zhang (ORCID: https://orcid.org/0009-0005-4150-711X)
- Cheng Zhen (ORCID: https://orcid.org/0000-0002-7750-1319)
- Jiong Zhang (ORCID: https://orcid.org/0000-0003-3402-0002)
- Xue Wu (ORCID: https://orcid.org/0009-0007-4684-2472)
- Yanan Chu (ORCID: https://orcid.org/0000-0002-9349-4307)
- Liteng Wang
Institutions
- China Pharmaceutical University (CN)
- Shanghai Jiao Tong University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Kidney Diseases
- Published
- 2024-08-16
- DOI
- https://doi.org/10.1159/000540107
- Citations
- 3
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- National Natural Science Foundation of China