Complete Response to Pembrolizumab in a Patient with Castration-Resistant Prostate Cancer with Both BRCA Positivity and a High Frequency of Microsatellite Instability: A Case Report
We herein report a case in which pembrolizumab treatment resulted in a complete response in a CRPC patient with both a BRCA2 mutation and an MSI-high status.
Authors
- Junichi Ohta
- Nobuhiko Mizuno
- Masatoshi Moriyama
- Takashi Kawahara (ORCID: https://orcid.org/0000-0002-7049-3379)
- Shusei Fusayasu
- Kazuhide Makiyama (ORCID: https://orcid.org/0000-0002-7449-2015)
- Yuta Karibe
- Hiroyuki Hayashi
- Takayuki Hirano
- K Yonezawa
- Jun Asano
- Hiroji Uemura
Institutions
- Yokohama City University Medical Center (JP)
- Yokohama Municipal Citizen's Hospital (JP)
- Yokohama City University (JP)
Publication Details
- Journal
- Case Reports in Oncology
- Published
- 2024-08-05
- DOI
- https://doi.org/10.1159/000540419
- Citations
- 2
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84