Detection of rare microorganisms in bone and joint infections by metagenomic next-generation sequencing
mNGS improves detection of rare pathogens in BJIs. mNGS testing reduces antibiotic-related complications, shortens hospital stay and antibiotic use duration, and improves treatment success rate, benefits which are particularly evident in culture-negative cases.
Authors
- Wenming Zhang (ORCID: https://orcid.org/0000-0003-1567-7279)
- Haiqi Ding
- Hongxin Hu (ORCID: https://orcid.org/0000-0002-4172-8458)
- Changyu Huang (ORCID: https://orcid.org/0000-0002-8377-9181)
- Yang Chen (ORCID: https://orcid.org/0000-0001-7168-7098)
- Xinyu Fang (ORCID: https://orcid.org/0000-0001-6337-8009)
- Jianhua Lyu (ORCID: https://orcid.org/0000-0003-4538-6181)
- Wenbo Li (ORCID: https://orcid.org/0000-0001-6131-8766)
- Chaofan Zhang (ORCID: https://orcid.org/0000-0001-7397-2298)
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Regional Medical Center (US)
- Putian University (CN)
Publication Details
- Journal
- Bone and Joint Research
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1302/2046-3758.138.bjr-2023-0420.r1
- Citations
- 9
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.15