Elucidating the genetic relationship between ulcerative colitis and diabetic kidney disease: a bidirectional Mendelian randomization study
This study underscores the intricate genetic interplay between UC and DKD, suggesting that individuals with UC may be at an elevated risk for developing DKD. Understanding these shared genetic pathways could facilitate the development of early detection strategies and targeted interventions for individuals at risk of DKD. Ultimately, these insights could lead to improved clinical outcomes for patients suffering from both conditions.
Authors
- Weijian Xiong (ORCID: https://orcid.org/0000-0001-6920-1909)
- Tai-Jun Zhang
- Hangxing Yu (ORCID: https://orcid.org/0000-0001-8347-193X)
- Yaping Guo
- Xili Wu (ORCID: https://orcid.org/0000-0001-8979-7674)
- Ying Li (ORCID: https://orcid.org/0009-0002-2891-9863)
Institutions
- First People's Hospital of Chongqing (CN)
- Yulin Orthopedics Hospital of Chinese and Western Medicine (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-08-15
- DOI
- https://doi.org/10.3389/fendo.2024.1435812
- Citations
- 2
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- Chongqing Postdoctoral Science Foundation
- Centre Scientifique et Technique du Bâtiment